More serious acid reflux can be treated with additional oral medications, more commonly used drugs include: 1, omeprazole, lansoprazole, rabeprazole and other proton pump inhibitors, which can significantly inhibit gastric acid secretion; 2, acid reflux corrosion damage to the mucosa of the stomach and esophagus, mucosal protective agents such as Daxil and aluminum thioglycollate can be used; 3, morpholine, mosapride, cisapride and other pro-gastric dynamics drugs, which can reduce the residence time of gastric acid in the stomach 3. Gastric stimulants such as morpholine, mosapride and cisapride can reduce the residence time of stomach acid in the stomach. The specific medication should be combined with the clinical and guided by the doctor’s face-to-face consultation.