Patients appear palm finger peeling cracking itching, may be by the manifestation of fungal infection, may also be caused by contact dermatitis, hand eczema and other diseases. 1. Fungal infection: fungal infection of the hands, also known as ringworm, mainly caused by fungal infection of the superficial skin of the hands, patients may appear palms and fingers peeling, cracking, blisters, thickening of the stratum corneum and so on, part of the patient accompanied by the symptoms of itching. 2. Contact dermatitis: when the patient’s hands contact with a certain allergen, may cause contact with the site or even outside the contact area of the skin inflammatory reaction, mainly manifested as multiple papules, blisters or even blisters, severe skin necrosis, ulcers, etc. The patient is often conscious of itching and burning, and the patient may also feel a sense of itching. Patients are often conscious of itching, burning, swelling and pain, etc. Palm finger peeling cracking itching may be caused by contact dermatitis. 3. Hand eczema: hand eczema is a hand skin inflammatory reaction, mainly manifested as hand itching, erythema, papules, blisters, flaking and so on, so the patient appeared palm fingers peeling cracking itching may also be caused by hand eczema. It is recommended that patients seek medical examination in a timely manner to clarify the cause of the targeted treatment, pay attention to hand care in life, to avoid violent scratching of the hands or prolonged immersion in water and other behaviors.