Whether a mole on the sole of the foot needs to be removed depends mainly on the location of the growth, the pattern of the rash, and the presence or absence of self-conscious symptoms. It is necessary to go to the dermatology department of a hospital for a clear diagnosis to determine whether it needs to be removed. Most moles are relatively safe and generally do not become malignant, but moles that grow in areas that are often rubbed or squeezed have a higher risk of malignancy, such as the forefoot, the bottom or edge of the toes, and the heel. Moles that appear in these areas are recommended to be cut off promptly to avoid malignant changes. Before a mole becomes malignant, there will be some changes in the skin rash, such as obvious darkening of the color, obvious enlargement of the size, redness around the mole, or ulceration, oozing or even pus flow from the mole, accompanied by itching, pain or burning sensation, etc. It is best to go to the hospital for surgical excision in time when the above symptoms appear. It is recommended that patients with moles on the soles of the feet go to the dermatology department of a regular hospital in time, and use standardized medication under the guidance of a doctor.