Due to the long-term use of immunosuppressive drugs, the patient’s body resistance is relatively low, so special attention should be paid to the prevention of colds within six months after transplantation. Do not go to crowded and noisy public places, especially during influenza. Wear a mask when necessary and go out, and seek immediate medical attention when cold symptoms are detected to avoid other serious complications. As the patient’s resistance decreases, the potential for infection increases. Do not approach pigeons, cats, dogs and other pets to avoid infection by other pathogens such as bacteria, fungi and viruses. 1, pay attention to hygiene, wash hands before and after meals, brush teeth in the morning and evening. 2, pay attention to dietary hygiene, food should be washed, meals should be cooked hot, do not eat spoiled food. 3, should do a good job of disinfection of the home environment, with things: (1) rooms and living rooms can be disinfected with ultraviolet light, once a day in the morning and evening. In winter, pay attention to opening windows and ventilation to keep indoor air fresh, and increase the number of UV irradiation disinfection if there are more guests coming and going during holidays. (2) The bathroom can be disinfected by wiping with 500 mg/L chlorine disinfectant, while paying attention to ventilation to ensure air quality. (3) Washing machine disinfection: bacteria will grow between the crevices of the washing machine after a long time, laundry should be washed separately, and the washed clothes should be put in the sun to dry, and the inside of the barrel should be rinsed with tap water after each use of the washing machine, and then rinsed with 500 mg/L chlorine disinfectant and rinsed with tap water if necessary. (4) Other items such as books and bedding should be frequently exposed to the sunlight, and pillow hearts are easily soaked with sweat and breed bacteria, so they should also be frequently exposed to the sun for disinfection. The principles of treatment of infection are to adjust the use of immunosuppressive drugs, reduce, suspend, stop (give up the transplant, save the patient’s life); strengthen the systemic support therapy, a small number of fresh blood transfusion, plasma transfusion, albumin and intravenous immunoglobulin infusion (IVIG); antibiotic use and selection, hold off until the results of bacterial examination. If empirical dosing has been initiated, choose broad-spectrum, targeting Staphylococcus, G-bacteria, and Listeria spp. After culture and drug sensitivity results, choose broad-spectrum antibiotics, highly sensitive and highly selective; consider nephrotoxicity, drug-immunosuppressant interactions.