Acyclovir ointment is not an adjunctive treatment for plantar warts. Plantar warts are mainly caused by human papillomavirus type I or type IV infection. Acyclovir ointment is mainly used to treat herpes simplex or herpes zoster infections. Therefore, acyclovir ointment is not an aid in the treatment of plantar warts. Mild pain, burning, tingling, itching, rash and other adverse reactions are seen after using Acyclovir Ointment. Its contraindications are unclear. Patients with plantar warts need to be treated by medication and physical methods. Medications commonly used include salicylic acid, fluorouracil ointment, imiquimod ointment, etc., all of which can have a therapeutic effect. You can also choose the physical methods such as freezing, laser, and electrocoagulation to eliminate them directly. It is recommended that patients with plantar warts go to the hospital in a timely manner and follow the doctor’s instructions for treatment to avoid delaying the condition.