Bile is a digestive fluid that has the effect of emulsifying fats but does not contain digestive enzymes. Bile-free feces are feces that do not contain bile or bile pigments. alpha 1 antitrypsin deficiency liver disease in newborns with hereditary alpha 1 antitrypsin deficiency develops cholestatic jaundice within the first month of life, with slow weight gain, lethargy, irritability, and bile-free feces. The stools are gray like clay, indicating that the passage of bile into the intestine has been blocked, and the bile has to be deposited in the skin through the blood circulation, making the skin yellow. Gallstones, bile duct cancer, pancreatic head cancer, liver cancer, etc. are all “roadblocks” to the flow of bile into the digestive tract. There is no bile in the digestive tract, and the stool is grayish-white clay-like. Relief methods are as follows: In addition to paying attention to the dietary taboos spicy food and greasy food cold food, need to go to the regular hospital for examination and related treatment according to the cause of the disease. Various liver diseases such as viral hepatitis, cirrhosis, hepatocellular carcinoma and other causes such as leptospirosis, sepsis, etc., can cause jaundice due to extensive damage to liver cells, which leads to grayish stools. Aggressive treatment of the cause is the key.