If the number of fire boils on the buttocks is small and not large, you can treat them with topical medications, such as mupirocin ointment, fusidic acid ointment, erythromycin ointment, iodophor, etc. If the number is large or the area is large, you need to take oral antibiotic treatment, such as cefdinir capsules, roxithromycin capsules, levofloxacin capsules, clarithromycin extended-release tablets, etc. You can also take oral Chinese anti-inflammatory drugs, such as Zhenhuang tablets, danshinone, sparing wind and detoxification capsules, etc. If the surface of the fire boil is soft and indicates more pus, it needs to be incised and drained, and oral antibiotics such as cefdinir capsule, roxithromycin capsule, levofloxacin capsule, etc. are needed along with the incision and drainage, and topical medication is also needed. After the boil on the buttocks, you need to eat a light diet, spicy and stimulating food and alcohol should be consumed as little as possible.