The warts can be treated with physical therapy, topical topicals and systemic medications. The temperature of liquid nitrogen is -196°C, which can cause ice crystals inside and outside the lesion cells and denaturation of cell membrane lipoproteins, thus causing the death of the lesion cells and tissues. Most warts can subside after 2-3 treatments. Those resistant to liquid nitrogen treatment can be treated with carbon dioxide laser or subcutaneous injection of 0.05%-0.1% bleomycin once a week. For drug therapy, topical application of a caustic chemical such as fire cotton gum or opium bark can be used topically. The treatment of plantar warts is more difficult compared to common warts because the local cuticle is thicker and the penetration of various treatments is poor, in addition to the frequent local pressure, so that the necrotic surface tissue sheds poorly after treatment and affects the treatment. The system medication, for part of the large extensive onset of patients, you can try the vitamin A class of drugs oral, such as isotretinoin capsules and vitamin E capsules.