The treatment of plantar warts includes local topical medication, physical therapy, and other treatments. 1. local topical medication: plantar warts are caused by human papilloma virus infection of the skin on the soles of the feet, local topical medication includes fluorouracil ointment, imiquimod ointment, vinpocetine ointment and so on, which has the function of peeling off, antiviral, regulating immunity and so on. The specific medication should be used according to the doctor’s prescription. 2. Physical therapy: Physical therapy includes laser treatment, freezing, electrocautery treatment, etc., which can be used to remove warts. 3. Other treatments: Other treatments include photodynamic therapy, which can be used for plantar warts that are not treated with conventional therapy. For persistent plantar warts, localized interferon injections can be used in conjunction with laser or cryotherapy. If the skin on your feet is abnormal and painful when pressurized, it is recommended to go to the dermatology department of a hospital to get a clear diagnosis and then cooperate with the doctor for treatment.