Atrial septal defect is one of the most common types of congenital heart disease, second only to ventricular septal defect, and is formed by a residual unclosed defect in the atrial septum during embryonic development. The majority of atrial septal defects are uniportal, a few are porous, and a very few are sieve-shaped. The ratio of male to female is 1.7:1. Interventional treatment: (1) usually ≥3 years old, weight ≥10 kg, ASD ≥4 mm and ≤36 mm with left-to-right shunt ASD; (2) distance from the edge of the defect to the coronary sinus, upper and lower vena cava and pulmonary veins ≥5 mm; to the atrioventricular valve ≥7 mm. There is a metallic blocking umbrella, which can be found on chest X-ray, fluoroscopy, CT and other examinations. Surgery: Surgical treatment is suitable for any type of atrial septal defect (unless the patient progresses to Eisenmenger’s syndrome inoperable) and can achieve almost 100% success rate in our hospital. Moreover, surgery in childhood can be done with a small incision in the right axillary or median lower sternal segment, with an incision length of only about 3 cm, which is concealed, safe and beautiful.