In newborn infants, transient jaundice, usually called physiologic jaundice, may occur due to the liver’s weak ability to convert and metabolize bilirubin, which means that the liver is not well developed. Physiologic jaundice is usually low in level and short in duration, and usually does not require special treatment and can subside quickly. If the jaundice lasts for a longer period of time and the level is higher, it is called pathological jaundice. For pathological jaundice, oral medications such as gardenia yellow can be used for treatment. If the effect is not satisfactory, further blue light irradiation can be considered, which can promote the transformation of bilirubin excretion and is a better way to eliminate jaundice. After these treatments, if the jaundice still does not subside, pay attention to exclude any special congenital diseases, such as congenital bile duct abnormalities, etc., which can be clarified by ultrasound and other examinations, and if necessary, exclude any acute viral hepatitis caused by viral infection, and further treatment according to different situations.