Hand, foot and mouth disease can generally be self-healing, mild patients can be given general treatment, serious patients under the guidance of the doctor to take antipyretic and analgesic drugs, glucocorticoids and other drugs for treatment. 1. General treatment: hand, foot and mouth disease can be cured, parents should let the child bed rest, drink more warm water, eat a light and soft diet, the child’s mouth pain pay attention to eat cold food. Pay attention to the child’s hygiene, protect the hands and feet of the skin and clothing, clean sheets, to avoid contamination of broken herpes, wash the hands of the child, and cut the nails short, in order to prevent scratching the rash and cause skin infections. 2. Antipyretic and analgesic drugs: When headache, fever, muscle pain and other symptoms occur, acetaminophen, ibuprofen and other drugs can be used under the guidance of the doctor as appropriate to relieve the symptoms. 3. Glucocorticoid drugs: when neurological involvement occurs, glucocorticoid treatment can be applied as appropriate, such as methylprednisolone, dexamethasone, etc., and after the condition is stabilized, it is necessary to reduce the dosage as soon as possible or discontinue the use of glucocorticoid. It is recommended that patients go to regular hospitals for treatment, should pay attention to hand hygiene and dietary hygiene in daily life, the above drugs should be taken under the guidance of a doctor.