Whether or not medication is needed for 24-hour urine protein quantification of 0.19g is related to the cause of urine protein. If it is physiological factors such as strenuous exercise, after resting, urine protein can turn negative, usually do not need drug treatment; if it is pathologic factors such as glomerulonephritis, urinary tract infections and other diseases caused by the need for drug treatment. The normal value of 24-hour urine protein quantification is less than 0.15g/24 hours for adults, and the 24-hour urine protein quantification of 0.19g is mildly high. It can be seen in physiological factors and pathologic factors. If it is caused by physiological factors such as strenuous exercise, fever, etc., after resting, the urine protein can usually turn negative on its own, without the need for medication; if it is caused by glomerulonephritis, urinary tract infections and other pathologic factors, it is usually necessary to take medication, you can take irbesartan, captopril, etc. to reduce the urinary protein as prescribed by the doctor, or oral levofloxacin and other anti-infective treatments. If the patient found that the 24-hour urine protein quantitatively elevated, it is recommended to go to the regular hospital in a timely manner, improve the examination to clarify the cause of the disease, under the guidance of the doctor to the targeted treatment or treatment.