What is the choice of treatment for women with Graves’ disease before pregnancy? If a patient with Graves’ disease chooses surgical thyroidectomy or 131 iodine therapy, the following are recommended: 1) If the patient has a high TRAb titer and plans to become pregnant within two years, surgical thyroidectomy should be chosen. This is because TRAb titers remain high for several months after the application of 131 iodine treatment, which affects the quality of the fetus; ② A pregnancy test is required 48 hours prior to 131 iodine treatment to verify pregnancy in order to avoid the radiation effects of 131 iodine on the fetus; ③ Pregnancy should not occur until 6 months after thyroid surgery or 131 iodine treatment. Replacement therapy with L-T4 (eugenol, etc.) is received at this stage to maintain serum TSH at 0.3 to 2.5 mIU/L levels. If patients with Graves’ disease choose antithyroid medication, the following are recommended: ① Methimazole (MMI) and propylthiouracil (PTU) have risks for both mother and fetus; ② MMI has the risk of fetal malformation, so it is recommended to stop MMI and switch to PTU before planning pregnancy; PTU is preferred during T1 of pregnancy and MMI is the second-line choice; ③ After T1, then switch to MMI to avoid PTU; ③ After T1, then switch to MMI to avoid PTU. switch to MMI to avoid the occurrence of hepatotoxicity of PTU.