First of all, it should be clear that alcohol has a damaging effect on the gastric mucosa, and drinking large amounts of alcohol is definitely bad for the stomach, so try to avoid large amounts of alcohol, severe stimulation, including spicy food and alcohol and other food stimulation. But if you have been drinking, the next day feel upset stomach, the most commonly used drugs include: 1, nausea: to use prokinetic drugs, including morpholine, Mosapride, Itopride, etc.; 2, stomach pain: If the performance is mainly stomach pain, usually to use gastric mucosa protective drugs or magnesium aluminum carbonate and other drugs to neutralize stomach acid; more serious may also be used to inhibit the stomach acid drugs, such as proton pump inhibitors. 3, after drinking a lot of alcohol in addition to the above measures to protect the gastric mucosa, the next day a light diet, pay attention to rest is also very important.