When it comes to smog disease, most people may associate it with smoking or haze, thinking that it is a disease caused by smoking or air pollution, and some people simply mistake it for a lung disease. It is an ischemic and hemorrhagic brain disease caused by progressive narrowing or even occlusion of the terminal and major branches of the internal carotid artery. The name “moyamoya disease” is due to the fact that cerebral angiograms show many small, dense piles of blood vessels that resemble the smoke exhaled during smoking. What is the formation of smoke-like blood vessels in smog? Smoky disease is not a strange disease, but a kind of cerebrovascular disease, which is a disease of blocked blood vessels in the brain. When the large blood vessels in the brain are blocked, the blood supply to the brain becomes insufficient. In order to ensure the blood supply to the brain, small, scattered blood vessels are created, a mass of capillary-like abnormal blood vessels that are different from normal. What can cause smog? The etiology of smog is complex and the true cause of the disease is not known. Based on clinical, pathologic, immunologic, and animal studies, it can be assumed that the disease is a group of acquired occlusive cerebrovascular diseases. Some of the possible associated factors include four main aspects: genetic factors, infection, inflammation and immune response, abnormal cytokine secretion, and elastin accumulation. It is now recognized that smog disease is clearly associated with abnormal autoimmune function. Is smog hereditary? Smog is not a typical genetic disease, but has a tendency to run in families. This means that if someone in the family has smog, the chances of having smog in the offspring are slightly higher. Therefore, it is important for family members of people with smog to be tested to rule out asymptomatic smog. What are the symptoms of smog? There are two main groups with a high incidence of smog: children around the age of 10, who commonly have confused speech, varying degrees of headache, irritability and irritability, etc. In addition, some children have low intelligence and slow development, and some are mentally abnormal. Early symptoms in adults are more obvious, such as different degrees of vomiting, dizziness, headache, numbness of the limbs, blurred vision, etc. Some patients also have more serious memory loss or general weakness, aphasia, epilepsy, etc. What tests are needed for smoker’s disease? Cerebral angiography (DSA) is the gold standard for the diagnosis of smog. It can reflect the morphological structure of cerebral blood vessels in a comprehensive manner, with clear images and high resolution, providing a true three-dimensional pattern for the observation of vascular lesions and the localization and measurement of blood vessel stenosis, further providing an accurate scientific basis for treatment. How can smog be treated? At present, the most effective treatment for smog is the application of surgical treatment (combined vascular bypass surgery), which can rapidly improve the blood supply to the brain by directly bypassing the intracranial and extracranial vessels to anastomose; at the same time, the brain surface can be plastered on a large scale to induce the formation of neovascularization, which provides a solid and powerful double guarantee for the brain blood supply. A wider range of improvement of blood supply to the brain surface was achieved, maximizing the surgical effect. Smoker’s disease is not an odd disease, nor is it rare, and in recent years it has occupied an increasingly important position in the etiology of stroke. Patients should seek timely medical attention if they develop the appropriate symptoms, and a good prognosis can often be achieved through early symptom screening, timely examination to confirm the diagnosis, and early surgical intervention.