Pemphigus is a relatively serious and easily recurring autoimmune herpetic disease, which can be treated with glucocorticoid drugs (such as betamethasone ointment), immunosuppressant drugs (such as cyclophosphamide), and biologic drugs (such as rituximab) as prescribed by the doctor in order to alleviate the itchiness and promote recovery. 1. Glucocorticoid drugs: you can follow the doctor’s instructions for external use of compound flumethasone cream, betamethasone ointment and other glucocorticoid drugs, to achieve the effect of inhibiting local inflammation and stopping itching. 2. Immunosuppressant drugs: you can take oral cyclosporine, cyclophosphamide and other immunosuppressant drugs to achieve the effect of lowering the body’s immune response and relieve itching. 3. Biological agents: patients with moderate to severe pemphigus can also be put on a drip of rituximab injection and other biological agents to reduce itching and promote the recovery of pemphigus. It is recommended that patients with pemphigus go to the hospital, follow the doctor’s instructions to standardize the treatment, do not blindly use their own medication, so as to avoid adverse reactions.