Mycoplasma infection causes fever and requires standard antibiotic anti-infective treatment. Early use of appropriate antibacterial drugs can reduce symptoms and shorten the course of the disease. Mycoplasma infections are self-limiting and in most cases can resolve spontaneously without treatment. Macrolides are the antibacterial drugs of choice, such as erythromycin, roxithromycin, and azithromycin. Quinolones, such as levofloxacin, gatifloxacin, and moxifloxacin, as well as tetracyclines, can also be used for the treatment of Mycoplasma pneumoniae, usually for a duration of about 2-3 weeks. Because Mycoplasma pneumoniae does not have a cell wall, antibacterial drugs such as penicillin or cephalosporins are not effective against mycoplasma. For violent choking cough, cough suppressants should be given. In case of secondary bacterial infection, targeted antibacterial drugs can be used for treatment according to the pathogenic examination.