The development of medical science has made us fully aware that the cause of cervical cancer is HPV, and in the past, talking about cancer has become a fear, but now for some female comrades, not only talking about cancer, but also talking about HPV has become a fear. Here, I would like to give you a clear message that cervical cancer has HPV infection, but HPV infection will not necessarily lead to cervical cancer. What should we do if there is HPV infection? For those who are purely HPV positive, NCCN does not recommend HPV screening for those under the age of 21 because women in this age group will most likely clear up on their own even if they are infected with HPV. According to guidelines published by the ASCCP in 2012, colposcopy is recommended for HPV 16 or 18 line infections, even though cytology is negative, because these two types are the most dangerous of the high-risk types. Treating HPV infections is often difficult. Low-risk HPV types usually cause genital warts, which can be removed with lasers and other physical methods. Those with high-risk types should primarily rule out possible intraepithelial cell carcinoma (precancerous lesions). Those who are positive for HPV high-risk types alone can be monitored. Certain medications may help promote HPV clearance, such as vaginal interferon, or the Chinese herbal medicine Povidon suppository. However, the effectiveness of these drugs still needs further clinical validation. The body can clear HPV by itself, but it may take 8-14 months. During this period, the clearance rate of the virus is 70-80%, and condoms should be used to prevent cross-infection or reinfection during observation or conservative treatment. You should also adjust your immunity, including exercise, nutrition, regularity, adjusting your mind, reducing mental stress and burden, and a healthy and hygienic sex life. For those who are older, such as older than 30 years old, and intend to have children in the near future, long-term observation is not recommended, but more aggressive treatment should be taken. It is advisable to check TCT every six months for pure high-risk HPV infection, and if abnormal TCT results are found, colposcopy and multi-point cervical biopsy should be done. Although there is little effective treatment for HPV, the HPV virus tends to stay in the cervical area with lesions. Removal of the lesion may result in the removal of HPV, which is known as “the cure is the virus”. However, HPV may also remain or integrate in cells without precancerous lesions, such as the squamous epithelium of the vagina or the columnar epithelium of the cervix. So although cervical lesions are removed, there is no guarantee that HPV is completely removed. In HPV-infected patients with cervical erosion, although TCT is normal, if the lesions can be removed with physical therapy, HPV may also be cleared with it.