A “Sinister Girl” popular in the north and south of the country Wang Zuxian recently appeared in Tokyo Disney Park, 49 years old, her recent photos are astounding, so that netizens can not help but sigh: her wrinkles have gone where? As the saying goes, the heart is born, maintain an optimistic and positive state of mind, less depressed and irritable negative emotions, the whole person will naturally become young and beautiful. However, in addition to this, facial wrinkles can also be reduced or eliminated through micro-plastic methods, such as injections of Botox, hyaluronic acid and other substances. In April 2009, the state approved botulinum toxin for wrinkle removal. Botulinum toxin is a biotoxin-based muscle relaxant that inhibits muscle contraction by inhibiting the release of acetylcholine and blocking nerve-muscle signaling, resulting in muscle relaxation paralysis to remove wrinkles. The amount of each injection is so tiny that it will not cause any effect on the human body. The safety is undoubted and it is the best method to remove power wrinkles at present. No recovery period is required after Botox injection, which does not affect normal work life. The effect maintenance time is generally 3-6 months, and can be injected again after wrinkle recurrence. Hyaluronic acid is an inherent component in human skin and will not cause allergic reactions. It can improve skin nutrient metabolism, make skin soft, smooth, remove wrinkles, increase elasticity and prevent aging. With the growth of age, smoking, sleeping squeeze and gravity traction, the content of hyaluronic acid in the facial skin decreases, which gradually reduces the collagen and elastic fibers in the dermis, causing skin relaxation and wrinkles on the face, and a variety of wrinkles can be effectively solved by hyaluronic acid injection, such as frown lines, crow’s feet, corners of the mouth and decree lines.