Itchy body after drinking belongs to the phenomenon of alcohol allergy, and most patients can cure themselves after stopping drinking, but some people who are intolerant to alcohol may have more serious symptoms and need to intervene with medications. Itchy body after drinking is mainly due to alcohol stimulation, which leads to the expansion of capillaries in the superficial dermis of the skin, and its expansion may induce mast cell degranulation and the production of histamine and other substances, thus causing itchy skin. For this condition, most patients can gradually relieve and disappear on their own after they stop drinking alcohol. Some patients who are intolerant to alcohol need to apply cold compresses with cold water or saline locally, and if necessary, topical application of glyburide lotion can be used, which can constrict local capillaries and thus relieve local itching symptoms. In addition, after drinking alcohol can not take oral antihistamines to treat allergies, otherwise it may cause adverse reactions. When itchy symptoms appear after drinking, you need to stop drinking immediately and drink more water to promote the body’s metabolism, and if necessary, intravenous drip to accelerate the metabolism of alcohol in the body.