Oral maxillofacial interstitial infection is a general term for purulent inflammation of the oropharynx, face and neck, usually acute purulent infection. Systemic symptoms include chills, fever, loss of appetite, peripheral discomfort, complications of sepsis, cavernous sinus thrombophlebitis, meningitis, toxic shock, etc. Maxillofacial interstitial infections have different treatment principles and treatment protocols according to the course of the disease. Acute plasma stage septic infection mainly has the following treatment process: 1, early on the principle of anti-inflammatory, in addition to systemic symptomatic treatment, anti-inflammatory and pain relief with antibacterial, sulfonamide, painkillers, etc.; 2, external application of gold powder, ichthyolite ointment, etc.; 3, the use of physical therapy, ultraviolet light, infrared, etc.; 4, the acute septic stage should be promptly incised and drained. If delayed self-breakage, the face will be left with obvious scarring, which will easily cause interstitial spread and deterioration of the disease process. After the inflammation subsides, the focal tooth should be extracted, and the gum and caries should be actively carried out and the focal tooth should be extracted. Inflammation of acute gland-derived tissues and boils, carbuncles and traumatic infections of the face and maxillofacial area should be treated promptly.