Mr. Gao, a 60-year-old man living in Tongnan County, Chongqing, had severe pain in his neck and upper extremities four years ago with no apparent cause, especially when he touched his neck or changed his position, and felt numbness in the palms of his hands. He was diagnosed with “intercostal neuralgia” at a local hospital, and the pain was relieved after treatment. But half a year ago, his condition suddenly worsened, and Mr. Gao was very distressed when treatment was fruitless. Three days ago, Mr. Gao had an MRI of the cervical spine at the local hospital, which showed an abnormal signal shadow in the bone marrow of the upper strength segment, considering the possibility of an occupying lesion, and a cavity could not be ruled out. In order to further treatment, the local hospital doctor suggested to transfer to a higher level hospital for consultation and treatment. So Mr. Gao came to the Department of Chiropractic Neurosurgery of the First Hospital of Chongqing Medical University. After examination, Professor Yan Yi diagnosed: trans-2-4 intramedullary plasmacytoma; coronary artery disease; and sequelae of cerebral infarction. In Mr. Gao’s case, Prof. Yan suggested that most of the C2-4 intramedullary tumor should be removed and a posterior cervical internal fixation should be performed. Mr. Gao agreed to the surgery. During the surgery, a tumor section was taken, suggesting “astrocytoma”, and the estimated size of the tumor was 50px*50px*37.5px. The surgery went smoothly. Half a month later, Mr. Gao was discharged from the hospital for further recovery at home. Prof. Yan introduced that astrocytoma is an infiltrative growth tumor, and most of the tumors may recur after resection, and after recurrence, the tumor may evolve into mesenchymal astrocytoma or glioblastoma multiforme. Seizures are often the first symptom, and 50% of patients have seizures. Most patients have headache, psychomotor muscle weakness, and vomiting with significant impairment of consciousness. The majority of patients have optic disc edema and cerebral neurological deficits on neurological examination. Nearly half of the patients present with limb muscle weakness, while a few patients present with speech difficulties, sensory disturbances, and visual field changes. Currently, astrocytoma advocates surgery as much as possible, followed by adjuvant radiotherapy and/or chemotherapy as appropriate; those who cannot be operated can be treated with stereotactic radiotherapy and/or chemotherapy.