The drug treatment of perianal abscess mainly includes oral antibiotics, topical anti-infective ointment, laxatives, pain relievers and so on. 1. Antibiotics can be applied jointly, such as cefixime and metronidazole. Allergic to two kinds of drugs is prohibited, and metronidazole is also prohibited in active central nervous system disease, blood disease, etc.. 2. Topical anti-infective ointment such as erythromycin ointment, allergic to the drug is prohibited. Usually used when abscesses are not formed, not necessary to use after the formation of abscesses. 3. Laxatives. For those who have difficulty in defecation, you can take laxatives such as lactulose oral solution, but it is prohibited for hypokalemia, lactose or galactose intolerance, gastrointestinal obstruction. 4. Analgesics. Analgesics such as celecoxib can be used if the local pain is severe. Contraindicated in allergy to the drug, pregnancy, lactating women, severe liver and kidney damage, myocardial infarction stroke history. Specific medications for perianal abscesses should be used in accordance with the doctor’s instructions.