English name: tadalafi
Medication class: other urologic drugs, including antispasmodics
[otw_shortcode_tabslayout tabs=”9″ tab_1_title=”Overview” tab_1_content=”Tadanafil is a phosphodiesterase type 5 (PDE5) inhibitor used to treat penile erectile dysfunction that requires sexual stimulation to make This product is not available for use in women.” tab_2_title=”Indications” tab_2_content=”Erectile Dysfunction” tab_3_title=”Dosage” tab_3_content=”The dosage varies when the drug is used to treat different indications. For adult men with erectile dysfunction, the dosage form is usually a tablet. It is a prescription drug and should be purchased with a doctor’s prescription and used as prescribed. Oral administration: 10 mg once before sexual intercourse (may be taken at least 30 minutes before sexual intercourse). The maximum dosing frequency is once a day and should not be taken continuously on a daily basis. Sexual stimulation is required for the product to be effective. If the effect of the medication does not meet your expectations, please consult your doctor or pharmacist and do not increase the dose yourself if possible, as overdose may lead to serious consequences. If you miss a dose, please do not take it at your own discretion and consult your doctor or pharmacist if necessary. The dose may be increased to 20 mg depending on efficacy and tolerability. It is not advisable to take it continuously every day. Please do not exceed this dose at the time of administration. OVERDOSAGE AND DAMAGE: Studies have found that single doses of up to 500 mg in healthy subjects and multiple doses of up to 100 mg per day in patients have similar rates of adverse events as lower doses. To ensure safety, if you overdose, seek medical attention and your doctor will take supportive measures (e.g., gastric lavage, emetic, saline infusion, etc.) as needed.” tab_4_title=”Precautions” tab_4_content=”Use of this product requires sexual stimulation as an instinctive response to treatment. There is no therapeutic effect of tadalafil when taken without sexual stimulation. Tadalafil does not prevent diseases that are transmitted through blood or sex, such as STDs or hepatitis. Please take safety precautions, such as using a condom. General Onset of Action: How long does it take to work Tadalafil is rapidly absorbed after oral administration and reaches maximum blood levels about 2 hours after taking the drug. Increase or decrease of dosage: how to increase or decrease the dosage and how to stop Tadalafil is a prescription drug and needs to be used according to the dosage prescribed by your doctor. Increase or decrease of dosage should be evaluated by your doctor and gradually increase or decrease the dosage under your doctor’s guidance.” tab_5_title=”Contraindications” tab_5_content=”Tadalafil is contraindicated in patients with hypersensitivity to tadalafil or any other excipients in this product and in children. The tablets contain lactose and are contraindicated in patients with hereditary galactose intolerance, galactolytic enzyme deficiency or glucose-galactose malabsorption. Tadalafil is not recommended if you have unstable angina or a history of angina attacks during intercourse, refractory arrhythmias, hypotension (<90/50mmHg) or refractory hypertension, myocardial infarction within the last 90 days, stroke within the last 6 months, or heart failure of New York Heart Association diagnostic criteria grade 2 or higher within the last 6 months. Tadalafil. Please take it under medical supervision. ” tab_6_title=”Adverse Reactions” tab_6_content=”Conditions requiring urgent discontinuation and immediate medical attention: If you experience sudden hearing loss, sudden deafness, sudden blindness (in one or both eyes), or erections lasting 4 hours or longer while taking this medication, you should discontinue the medication and seek immediate medical attention. Possible adverse reactions: In addition to treating your disease, the medication may also cause you some discomfort. Some of the adverse reactions may disappear in the course of drug use. When you encounter adverse reactions that affect your life, you should communicate with your doctor and pharmacist in time Common: headache, dizziness, back pain, myalgia, nasal congestion, indigestion, etc. Rare: sudden hearing loss, sudden deafness, sudden blindness (in one or both eyes), prolonged erection, etc. Very rarely: swollen eyelids, or described as eye pain and conjunctival congestion, etc.” tab_7_title=”Interactions” tab_7_content=”Drugs are affected by food, other drugs taken at the same time, as they take effect in the body or are metabolized out of the body. Some effects may enhance or diminish the effectiveness of the drug. Some effects may also cause you to have adverse drug reactions and should therefore be noted. Foods that may affect the medication: Drinking alcohol while taking the medication may make you more susceptible to upright hypotension, which may be characterized by dizziness and a feeling of vertigo upon standing up, so avoid drinking large amounts of alcohol and alcoholic beverages while taking the medication. Grapefruit juice can increase the toxic effects of tadalafil. It is best to avoid grapefruit (also known as grapefruit) and its products after taking this medication. Other drugs that may affect this medication: Potent cytochrome P450 (CYP) 3A4 inhibitors (e.g., ketoconazole, erythromycin, itraconazole, ritonavir. When tadalafil is combined with these drugs, it can increase tadalafil exposure. If you must use a combination drug, it is recommended that you take it as needed. The recommended maximum dose of this product is 10 mg no more frequently than once every 72 hours; the recommended maximum daily dose of this product is 2.5 mg once a day. Nitrates (e.g., nitroglycerin, isosorbide nitrate) and guanylate cyclase agonists (e.g., liothyronine). When tadalafil is combined with these drugs, it may enhance the antihypertensive effect and lead to hypotension, so the combination is prohibited. Alpha-adrenergic receptor blockers (e.g., alfuzosin, terazosin, tamsulosin). When tadalafil is combined with these drugs, it can significantly lower blood pressure and lead to symptomatic hypotension (e.g., syncope). Please use caution when combining. Before using this product, wait until treatment with alpha-adrenergic receptor blockers has stabilized before starting this product, and the combination should be started at the lowest recommended initial dose. Other antihypertensive agents (amlodipine, angiotensin II receptor blockers, bendroflumethiazide, enalapril, metoprolol). When tadalafil is combined with these drugs, the antihypertensive effect may be slightly enhanced. Please pay attention to the monitoring of blood pressure when combined. Antacids (e.g., magnesium hydroxide, aluminum hydroxide). When tadalafil is combined with these drugs, it may significantly reduce the absorption rate of this product, but has no effect on the exposure of this product. CYP 3A4 inducers (e.g., rifampin, phenobarbital, phenytoin, carbamazepine). When tadalafil is combined with these drugs, exposure to this product can be reduced. No dose adjustment is needed when used in combination. However, avoid this product if you are a patient who requires long-term use of a potent CYP 3A4-inducing drug. Note that hemodialysis does not have a significant clearance effect on this product.” tab_8_title=”Special Populations” tab_8_content=” Pregnant/Lactating Elderly Infants Drivers Patients with Renal Insufficiency No dose adjustment is needed for mild to moderate renal insufficiency. The recommended maximum dose for severe renal insufficiency is 10 mg Patients with hepatic insufficiency Patients with spinal cord bundle injury, previous pelvic surgery, and prostatectomy Patients with pulmonary veno-occlusive disease Patients with severely impaired autonomic control of blood pressure, left ventricular outflow tract obstruction (e.g., aortic stenosis, idiopathic hypertrophic subaortic stenosis) Patients with significant aortic and left atrioventricular valve disease, pericardial constriction, restrictive or congestive Patients with cardiomyopathy, significant left ventricular dysfunction, symptomatic coronary artery disease Patients with inherited degenerative retinal disease (including retinitis pigmentosa) Patients with bleeding disorders, active peptic ulcer, or patients with risk factors for developing non-arteritic anterior ischemic optic neuropathy (NAIN) ” tab_9_title=”other” tab_9_content=”drug Properties 20mg tablets are yellow, almond shaped and marked with “C20″ on one side. Common Specification 20mg. Reference Price $200.67 – $445.00 Storage Method Room temperature.”] [/otw_shortcode_tabslayout]