First of all, let’s popularize what is premature ejaculation: there are many definitions of premature ejaculation, mainly referring to the short time of sexual intercourse that is ejaculation, and some can not complete sexual intercourse at all. In some cases, ejaculation occurs before the penis comes into contact with the woman, or just touches the woman’s vulva or vaginal opening, or less than 2 minutes after vaginal insertion, and the penis then weakens after ejaculation and cannot maintain a normal sexual life. Secondly, what tests should we do after finding premature ejaculation? My suggestion is that we should have a simple, comprehensive examination at the first visit to rule out possible risk factors or co-existing diseases. These factors can cause premature ejaculation, aggravate premature ejaculation or comorbidities of premature ejaculation. 1. Specialist physical examination Physical examination is necessary for the initial evaluation of premature ejaculation in order to identify premature ejaculation or other sexual dysfunctions, especially underlying diseases related to erectile dysfunction. Premature ejaculation and erectile dysfunction are often concomitant disorders. These examinations include examination of male secondary sexual characteristics, penis, testicles and epididymis, and sometimes even ultrasound examination of prostate and seminal vesicles is required. 2. Urinalysis When a UTI is suspected, a routine urinalysis should be performed first to determine if a urinary tract infection exists. If necessary, a urine bacterial culture, mycoplasma, chlamydia, gonococcus and other tests should be performed to determine the causative agent. Although the causal relationship and mechanism between prostatitis and premature ejaculation is not clear, current research suggests that prostatitis may be one of the risk factors for premature ejaculation and should be given proper examination and treatment. 4. Blood sex hormone examination Changes in blood sex hormone levels may lead to premature ejaculation and are associated with erectile dysfunction, and testing of sex hormone levels such as testosterone and prolactin is recommended when erectile dysfunction is present in combination. 5. Thyroid function test Although hyperthyroidism is one of the risk factors for premature ejaculation, thyroid function test is not recommended for patients with premature ejaculation. Symptomatic hyperthyroidism is easily detected by clinical observation (irritability, tremor, night sweats) and heart rate monitoring, and thyroid hormone level testing is performed only when necessary. 6. Neurophysiological examination Neurophysiological examination includes measurement of penile vibratory sensation and sensory evoked potentials of the dorsal penile nerve. It is especially important to emphasize that the current national and international guidelines for the treatment of premature ejaculation agree that neurophysiological examination should only be completed under the guidance of specific results of medical history or physical examination. Finally, after talking about so many examination items above, you may be dazzled and unable to choose. It’s okay, don’t bother your brain, leave all these questions to your doctor, take the first step, walk into my office and say goodbye to the “rush”.