Right chest tightness and pain after smoking may be caused by physiological factors, but also due to diseases, such as tuberculosis, costochondritis, pleurisy and other diseases. 1. Physiological factors: have bad habits, smoke too much, in the smoke stimulation may lead to the right chest chest pain, reduce the frequency of smoking will slowly get better. 2. Tuberculosis: when tuberculosis bacillus infection will lead to tuberculosis, when tuberculosis bacillus stimulate the lungs, there may be symptoms such as chest tightness and pain in the right chest, which will be aggravated after smoking. It can be treated with anti-tuberculosis drugs such as isoniazid under the guidance of doctor. 3. Costochondritis: when the costal cartilage is stimulated by inflammation, there may be symptoms of tightness and pain in the right chest, which will be aggravated after smoking. It can be treated with antibiotic drugs such as cephalosporin and penicillin under the guidance of a doctor. 4. Pleurisy: Virus, bacteria and other infections may induce pleurisy, which may lead to right chest tightness and pain, and the pain will be aggravated after smoking. You can take ibuprofen and other anti-inflammatory painkillers under the guidance of a doctor. It is recommended to consult a doctor and quit smoking after smoking.