Who is PGS for? 1.Pregnant women of advanced age (age ≥ 35 years) 2.Pregnant women with a history of recurrent spontaneous miscarriage (spontaneous miscarriage ≥ 3 times) 3.Pregnant women with recurrent embryo implantation failure (failure ≥ 3 times) 4.Couples who have given birth to children with chromosomal abnormal diseases 5.Couples with abnormal chromosome number and structure 6.Couples with strong intention Is PGS a panacea? After choosing PGS, routine prenatal checkups should not be neglected. Because there are more than 4,000 kinds of various genetic diseases worldwide, and at present, PGS can only check for abnormalities in the structure and number of 23 pairs of chromosomes in embryos, which cannot cover all diseases. Although this does not affect the normal development of the embryo, the genetic composition of the cells taken and those left behind for further development are not identical, so the screening results may not match for some chromosomal chimeric diseases. In addition, the cause of chromosomal disorders is still unknown and there is no way to prevent them. Although healthy embryos are selected, chromosomal changes may occur at any stage of fetal development after embryo transfer due to maternal and environmental factors. Therefore, after choosing PGS for successful conception, pregnant women still need to undergo routine prenatal screening. PGS is not a substitute for prenatal screening. If fetal abnormalities are found during routine prenatal checkups, or if the pregnant woman herself has indications for prenatal screening, she is strongly advised to choose prenatal screening methods such as amniocentesis for confirmation.