Erythromycin can be used on the vulva for topical application and is often used in the treatment of vulvodynia and vulvar boils. Erythromycin ointment has anti-inflammatory and pain-relieving effects, as well as a certain lubricating effect, which is helpful for the recovery of the disease. If women experience simple vulvar itching, local redness and swelling, as well as vulvar pain, they should promptly go to the hospital gynecological examination. If vulvodynia or vulvar boils are diagnosed, local application of erythromycin can be used for more effective treatment. The main role of erythromycin is anti-inflammatory and antiseptic, which is more effective for bacterial infections, but has little effect on eczema and fungal infections. Therefore, for women with vulvar eczema, or vulvar skin infected with fungus, using erythromycin for application has no therapeutic effect. In addition, the treatment of vulvar inflammation can be supplemented by washing the vulva with compound cypress lotion or Chuan Bai anti-itch lotion and then applying it topically. When treating vulvar boils, you need to use povidone iodine solution for local disinfection before applying erythromycin, which will be more effective in treatment. In addition, women need to keep their vulva clean and dry in daily life, eat more food with higher protein content, and exercise properly to strengthen their resistance. Sexual intercourse should be prohibited during the treatment period to avoid aggravating the inflammation.