You can take folic acid all the time during pregnancy, but it is recommended to choose the right dose of folic acid according to different conditions. Everyone feels differently about folic acid. Some people take folic acid which causes loss of appetite and mental atrophy and some do not feel it. In general, folic acid supplementation is recommended for the first 3 months of pregnancy and the second 3 months of pregnancy to provide essential nutrients for the development of the fetal central nervous system and to prevent fetal neural tube abnormalities, as well as to promote the production of red blood cells and prevent anemia during pregnancy. However, if a pregnant woman is diagnosed with TT type of folic acid gene, suggesting that the enzymatic activity of folic acid is relatively low and the absorption of folic acid is particularly poor, she can take or increase the dose of oral or orally active folic acid throughout pregnancy under the guidance of her doctor to avoid folic acid deficiency that may lead to fetal developmental malformations, congenital heart disease, anencephaly or cleft lip.