The therapeutic drugs for purpura nephritis with blood creatinine 98μmol/L mainly include anti-allergic drugs, hormonal drugs as well as immunosuppressants, antihypertensive drugs and so on.
Purpura nephritis in the acute stage need to carry out anti-allergic treatment, can apply anti-allergic drugs such as chlorpheniramine, etc., try to avoid contact with allergens. For most patients, the disease is self-limiting. Therefore, for most patients with mild clinical manifestations and transient abnormalities in urinalysis, the disease will improve on its own within a short period of time without special treatment.
For patients with definite renal damage, treatment with hormones can be considered, commonly used are prednisone acetate and methylprednisolone. If the pathological type of purpura nephritis is serious, it is necessary to apply high-dose hormone shock therapy, if the therapeutic effect is unsatisfactory, it can be combined with the use of immunosuppressant treatment, commonly used immunosuppressants are cyclophosphamide, tacrolimus and so on.
Patients with purpura nephritis should pay attention to controlling high blood pressure, and can use ACEI or ARB drugs such as captopril and irbesartan to lower blood pressure, reduce urinary protein and protect renal function.
All of the above medications should be used under the guidance of a doctor, avoid self-medication. Patients with purpura nephritis are advised to go to regular hospitals in time for targeted treatment or therapy under the guidance of doctors.