Panic at 5:00 p.m. may be due to hypoglycemic reaction and cardiac arrhythmia, and it is recommended to be treated by general treatment and medication after the cause is clarified. 1. Hypoglycemic reaction: Some patients may eat less at lunch due to personal factors or eat unreasonable types of food, and eat high fat food alone, then at 5:00 p.m., the glucose content in the blood is less, and there will be symptoms of hypoglycemia, such as panic, sweating, fatigue, hunger, etc. It is recommended to adjust the dietary structure in time, and to increase the volume of meals and the proportion of carbohydrates in an appropriate amount. 2. Arrhythmia: some patients may be due to a day of work, more tired, 5:00 pm sympathetic nerve excitation, arrhythmia, such as ventricular premature beats, atrial premature beats, etc., this situation needs to be at noon to take appropriate rest, if there are still recurrent episodes of the need to comply with the doctor’s instructions for oral drug therapy, such as metoprolol, bisoprolol and so on. If you have a panic attack at 5 p.m. that cannot be relieved by improving your lifestyle, it is recommended that you go to the hospital in a timely manner to clarify the cause of the problem and then undergo targeted treatment.