If you have been trying to conceive for many years and are not pregnant, it is recommended to have a timely and detailed examination to clarify the diagnosis and then target treatment. It is recommended for the woman to have blood tests for sex hormone six and thyroid function on the 2nd-3rd day of menstruation. When the period is completely cleared, gynecological examination is recommended to find out whether there are abnormalities in the vulva, vagina, uterus and pelvis and to clarify whether there is local inflammation. Ovulation monitoring is started on the 12th day of menstruation to find out if the ovulation function is normal. If all the above examinations are normal, another ultrasound examination is needed one week before menstruation to detect endometrial thickness and to alert for inactive endometrial tuberculosis or endometrial adhesions caused by previous uterine surgery such as curettage or post-abortion. The male partner also needs to be examined. The male partner should also be examined for normal sperm quality by performing a routine semen examination with 3-5 days of abstinence. After the above examination, the specific cause of non-pregnancy will be clarified and the treatment will be targeted in time. When preparing for pregnancy, couples should pay attention to maintaining a regular lifestyle, pay attention to personal hygiene, avoid staying up late, and keep a happy mood, etc. If necessary, it is recommended to go to the infertility department of a regular hospital for examination and treatment.