Chest tightness and shortness of breath, swelling of lower limbs and constipation can be seen in the decompensated stage of liver cirrhosis, heart failure, renal failure, pulmonary heart disease, etc., which requires timely medical treatment. 1. Liver cirrhosis decompensated stage, due to liver decompensation and portal hypertension, resulting in sodium retention, ascites production, hemorrhoidal venous dilatation, hypersplenism, hepatopulmonary syndrome, etc., resulting in dyspnea, cyanosis, double lower limb edema, constipation, can also be manifested as gastrointestinal hemorrhage, jaundice of the skin. 2. Heart failure, such as acute left heart failure, weakened cardiac contractility, pumping dysfunction, causing exertional dyspnea, hemoptysis, cyanosis, constipation, and in severe cases, pulmonary edema and hepatomegaly. Right heart failure can also cause dyspnea, due to the body venous pressure increases, resulting in systemic soft tissue edema, mostly low hanging parts of the concave edema, such as double lower extremity edema. 3. Water and sodium retention in renal failure, manifested by the appearance of subcutaneous edema and body cavity effusion of varying degrees, accompanied by heart failure, which may be manifested as loss of appetite, hypertension, chest tightness and shortness of breath, lower extremity edema, constipation, etc. 4. Dyspnea, shortness of breath, chest tightness, edema of both lower limbs due to pulmonary hypertension and right heart insufficiency, constipation, etc. can be seen in the late stage of pulmonogenic heart. Chest tightness, shortness of breath, lower extremity edema, constipation and other conditions are diverse, if not actively treated will lead to serious consequences, should be timely medical consultation.