Atresia syndrome: also known as atresia or deafferentation, is a clinical syndrome caused by lesions at the base of the cerebral bridge. Clinical features 1, the patient can not speak, quadriplegia, cerebral nerve paralysis below the cerebral bridge, manifesting bilateral complete facial and tongue paralysis, expression loss, swallowing reflex disappeared, and only the vertical movement of the eyeballs and convergence are preserved. 2.Patients are conscious, language understanding is not impaired, and up and down movement of the eyeballs can be used to indicate. Since the patient cannot speak and cannot move his body, it is easy to be misdiagnosed as coma. 3.Electroencephalogram is normal or mild slow wave changes, which can be differentiated from consciousness disorder. Clinical significance Atresia syndrome is mainly seen in: 1, vascular lesions of the brainstem (mostly infarction or hemorrhage on the ventral side of the cerebral bridge) 2, injury to the cerebral bridge, demyelinating changes, inflammation and tumors.