Prevalence: The NHSLS (USA) study showed that the prevalence of PE by age group was 30% (18-29 years), 32% (30-39 years), 28% (40-49 years) and 55% (50-59 years). This high statistical prevalence may also be related to the questionnaire design (“yes/no” type two) and the selection of the study population. The European Waldinger statistic by four types of PE was 2.3% primary, 3.9% secondary, 8.5% variant and 5.1% PE-like erectile dysfunction. A large sample showed that the incidence of primary and secondary PE was 5%, which is consistent with the results of 5% of the population with an ejaculatory latency of less than 2 minutes. Etiology: not clear. Physiological-psychological hypotheses such as anxiety, hypersensitivity of the penile head, and 5-HT receptor dysfunction. There is limited information to support these theories. Risk factors: Anxiety is more frequent in ED, and the rate of PE is also higher. Unlike the ED, however, the incidence of PE does not correlate with age. Race is more common in black, Hispanic men and Islamic men. Education The incidence of PE is higher at low levels of education. Other Genetics, poor general health, obesity, prostatitis, thyroid hormone disorders, psychological factors, and excessive stress, history of traumatic sexual experiences, etc. No significant effect on marriage or income. Impact on the quality of life: inability to obtain relaxation and pleasure from sex, can reduce the frequency of sex, low confidence, hinder interpersonal relationships with partners, can lead to worry, anxiety, embarrassment and frustration. The negative effects are not limited to the disease itself. Despite the severe psychological and quality of life effects of PE, only a minority of people seek medical attention. Diagnosis: Judgment is based on medical and sexual history. If PE is considered, it is then categorized as primary or secondary. Pay attention to whether it is situational (specific environment or specific partner) or persistent. Note the latency of ejaculation, the intensity of sexual stimulation, the impact on quality of life, and the presence of inappropriate drug and substance use. Special attention is paid to distinguishing between PE and ED. In many patients with ED, PE occurs because of anxiety caused by erectile dysfunction, and in some patients, penile weakness after premature ejaculation is considered ED, but is actually PE. Vaginal ejaculation latency (IELT) measurement: IELT has an overlap zone between PE and healthy individuals, and cannot be used as the sole basis for diagnosis. Stopwatch timing significantly affects ejaculatory self-control, and has less impact on PE-related distress or sexual satisfaction. In clinical practice, the sensitivity and specificity of PE diagnosis based on self-assessment and stopwatch timing are 80%. Combining ejaculatory self-control and satisfaction with intercourse increases the diagnostic specificity to 96%.