Primary trigeminal neuralgia, facial spasm, and glossopharyngeal neuralgia are collectively referred to as cranial nerve disorders, and their etiology is primarily due to compression of cranial nerves in and out of the brainstem region by abnormal blood vessels. Microvascular decompression is the best known option for the complete treatment of this group of diseases. Trigeminal neuralgia is mainly manifested by recurrent paroxysmal severe pain in the trigeminal nerve distribution of one side of the face. The pain lasts for a few seconds or minutes and is periodic, with intervals between attacks as in normal people. The attacks are often unpredictable, and each pain attack lasts from a few seconds to 1 to 2 minutes and stops abruptly. The nature of glossopharyngeal neuralgia is similar to trigeminal neuralgia, but the site of onset is mainly deep in the throat or deep in the ear canal. The pain in both disorders is very intense, and in severe cases the patient feels unbearable pain. Facial muscle spasm is an intermittent involuntary twitching of one side of the face. Facial twitching usually starts in one eyelid area and can gradually extend to one side of the face. Microvascular decompression is a delicate procedure performed under a microscope. Our department has safely performed more than 500 cases of this type of surgery since 2007. Under the guidance of the concept of precise neurosurgery, with the gradual introduction of 3.0T MRI machine, German Zeiss OPMINeuro operating microscope, neuroendoscope and intraoperative neurophysiological detection system, the efficiency of this surgery in our department can reach 97%, which is in the leading position in northwest China and advanced level in China.