Medications for headaches include non-steroidal anti-inflammatory drugs such as ibuprofen, and there are also medications such as sumatriptan and dihydroergotamine, which are used to treat headaches caused by upper respiratory infections, migraines, cluster headaches, and other conditions. Treatment of headaches needs to be tailored to the cause. 1. Upper respiratory tract infection: when upper respiratory tract infection, due to inflammatory mediators have the effect of vasodilatation, so the patient may appear headache symptoms, this situation can be treated with acetaminophen, aspirin, ibuprofen and other non-steroidal anti-inflammatory drugs to alleviate headache. 2. Migraine: Migraine is a chronic neurovascular disease, patients can appear unilateral throbbing severe headache, the onset of the disease may be related to genetic, endocrine and psychiatric factors, the treatment, you can use non-steroidal anti-inflammatory drugs, such as diclofenac, but also the use of 5-hydroxytryptamine agonists, such as sultanapine, but also the use of ergot alkaloids, ergotamine and other drugs. 3. Cluster headache: cluster headache is a kind of autonomic headache, patients can appear fixed in one side of the eye and around the severe headache, treatment can use zolmitriptan and other 5-hydroxytryptamine receptor agonists, but also can use ergot alkaloids such as ergotamine, but also can be used to relieve the headache of the medication such as miridocaine. If you experience headaches, you should seek medical attention to identify the cause and standardize treatment.