Scabies is a contact infectious skin disease caused by scabies parasites in the epidermis of human skin. The scabies mite belongs to the class of mites, so it is also called the scabies mite and is parasitic in the skin of humans and mammals. The infection of scabies is transmitted by direct contact (including sexual contact) or indirect contact between people, such as the contact method of living in a bed and shaking hands, or indirect infection by touching the clothes, bedding, sheets, pillowcases, towels, etc. used by the patient. Therefore, the disease occurs mostly in people with poor hygiene conditions and close living contact, especially in people living in groups, such as boarding students and migrant workers, and often in a family with multiple members. After the scabies mite invades human skin, in addition to mechanical stimulation of the skin, the toxin secreted by the scabies mite can also cause skin metamorphosis, causing papules, blisters or pustules on the skin, while causing strange itching. The scabies mite usually likes to invade delicate parts of the skin, such as finger crevices, wrists, elbow sockets, armpits, under the nipples, vulva, groin, etc. The damage to the skin by the scabies mite is not only manifested as tunnels (where the scabies mite burrows, showing a tiny gray or black line), papules, blisters, and pustules, but also nodules the size of green beans to soy beans can appear after infection in the penis, scrotum, labia, and perianal area. The proverb says: “scabies is a dragon, first from the hand slit line, around the waist turn three circles, the pubic camp”. This very graphically describes the general characteristics of scabies. “Scabies is a dragon”: it means that the symptoms of scabies are generalized, not concentrated in a certain place, and it also means that scabies has a developmental nature, often itching indefinitely, like a dragon going through; “first from the hand seam”: the hand seam is the first part to be affected; “three circles around the waist”: the waist is often the main site of the disease; “the pubic area is camped out”: scabies often ends up with scabies nodules in the pubic area. The itching symptoms of scabies patients often intensify at night, which is due to mechanical irritation caused by female worms starting to dig tunnels at night. In some patients, stimulation such as scratching and water scalding due to itching can cause epidermal exfoliation, blood crusting or secondary infection, resulting in folliculitis and boils. A small number of patients can also be complicated by nephritis. Scabies should be treated immediately in isolation in order to completely eliminate the source of infection. The clothes worn by the patient, used bedding and other items must be disinfected by boiling or exposed to the sun to kill the scabies mite. The treatment of scabies is mainly based on external medicine, and generally does not require systemic medicine. If the combined infection or eczema, etc. can also be treated with internal medication. Topical medication commonly used sulfur ointment, such as adults with 10% sulfur ointment, children with 5% sulfur ointment, morning and evening coated once. Special attention should be paid to the fact that the ointment should be applied all over the skin of the body except the scalp and the face, and carefully applied at the papules and blisters. Do not bathe or change your clothes during the rubbing period, and use the medicine for 3-4 days continuously. In order to keep the drug at a certain concentration, take a thorough bath after 4 days. Change of clothes, bedding, etc. should be disinfected. Generally, it can be cured after 1-2 courses of treatment, and the treatment time for scabies in children should be extended appropriately because the concentration of the selected drug is lower in children, and allergic lesions due to hypersensitivity reactions in children will last longer. Observe the treatment for 2 weeks after the end of treatment to determine the efficacy. If there is a recurrence, it should be treated promptly. Prevention of scabies, first of all, we should pay attention to personal hygiene, bathe, change clothes and bedding regularly, do not live with the patient, shake hands, and do not use the patient’s clothes, bedding, etc. Patients found should be treated in a timely manner, and clothes changed should be boiled to exterminate insects, and things that cannot be boiled and scalded should be wrapped in plastic for a week and then washed after the scabies mites are starved.