There is no clear connection between estradiol, progesterone and HCG, but according to the fluctuation of their values, they can indicate different states that pregnant women are in, such as normal pregnancy, ectopic pregnancy, embryonic dysplasia, etc. 1. Normal pregnancy: women’s estradiol, progesterone and HCG levels gradually increase in early pregnancy, the progesterone level in pregnant women in early pregnancy should not be lower than 20ng/ml, while estradiol is normally around 0-300ng/L. And for HCG, usually HCG >5U/L can be considered as possible pregnancy, and its secretion is around 100-500IU/L at 4 weeks of menopause and 8-10 weeks. For HCG, usually HCG>5U/L can be considered as possible pregnancy, about 100-500IU/L at 4 weeks of menopause, and its secretion reaches a peak at 8-10 weeks of menopause, which can be about 15000-200000IU/L; 2, ectopic pregnancy: if the value of the three is significantly lower than the level of early intrauterine pregnancy in early pregnancy, and the pregnant woman is accompanied by adnexal area If the values of estradiol and blood HCG doubling are relatively low, but progesterone is high, it is necessary to consider the possibility of embryonic dysplasia. The above three hormones play a key role in the normal development of early embryo, any low value may cause miscarriage, so you need to go to the hospital for regular maternity checkups on time to avoid early pre-miscarriage.