Azithromycin is an antibiotic. The principle of hemorrhoid formation is mainly the local submucosal congestion and edema in the perianal area, as well as the formation of blood clots or varicose veins. Oral azithromycin or intravenous azithromycin is not effective in acute attacks of hemorrhoids. The main treatment for hemorrhoids is topical professional hemorrhoid medication and oral medication, you can choose to take oral Mai Zhi Ling tablets, anal plug Jiuhua hemorrhoid suppositories or Indomethacin Sanchi ice suppositories to reduce swelling and pain, and apply Jing Wan Hong hemorrhoid cream to the anal opening. If the pain or bleeding is severe, you can also take oral hemorrhoid pellets or hemorrhoid capsules to stop the bleeding. You need to pay more attention to choose water to cleanse the perianal area after each bowel movement to avoid the residue of feces or inflammatory substances that can aggravate the condition of hemorrhoids.