How to prevent the occurrence of peritoneal infection is the most important concern of the majority of kidney failure peritoneal dialysis patients, our nephrology department since 1998 to carry out peritoneal dialysis, the diagnosis and treatment of a large number of patients with chronic kidney failure, the current online dialysis patients nearly 300, the number of patients in the province ranked second, I have accumulated a modest experience in more than a decade of work, and share with you, in order to help patients with peritoneal dialysis. 1, peritoneal dialysis environmental requirements: patients preferably live in separate rooms. The room should be well-lit, clean and dry, with the air disinfected with ultraviolet light at least once a day, with an effective exposure time of more than 30 minutes each time, and the operating table and floor wiped with chlorine-containing disinfectant. 2. Dialysis solution is heated to 37℃ with dry heat thermostat or dry heat thermostat package. Do not overheat or overcool. 3.Strictly wash hands and bring a sterile mask before the fluid exchange operation. 4.Strictly aseptic operation and safe fluid exchange operation, including preparation, connection, drainage, flushing, perfusion and separation before fluid exchange. 5.Observe the balance of dialysis fluid in and out, the nature of dialysis fluid: such as color, presence of flocculent, turbidity, etc.; pay attention to observe whether there is redness, swelling, heat, pain, secretion, etc. at the outlet of the catheter, and deal with it timely if found. 7, encourage the patient to move, but avoid strenuous and increased abdominal pressure exercise. 8.Patients into high quality high protein, high vitamin diet. Protein intake 1,2~1,5g/kg, d, mainly animal protein, such as: milk, lean meat, eggs, etc. Eat more vegetables and fruits. Because a lot of nutrients (such as vitamins, trace elements and proteins) are lost during the process of abdominal dialysis, many abdominal dialysis patients have poor appetite and malnutrition. I believe that under the premise of adhering to dietary guidance, should be based on the patient’s personal diet wash good, appropriate relaxation, in order to increase appetite, encourage eating, improve the patient’s nutritional status for the purpose. 9, the patient is regularly followed up, every 6 months to the hospital to replace the short tube of abdominal dialysis, 2-3 months to do the appropriate laboratory tests. In the process of home abdominal dialysis, poor drainage or abnormal nature and color of the effluent, abdominal pain, etc. are found in time to come to the hospital for consultation. 10, home abdominal dialysis process if found in the abdominal dialysis fluid bag broken, liquid leakage, please be sure not to break the bag of abdominal dialysis fluid into the abdominal cavity, otherwise it will greatly increase the incidence of abdominal infection. Patients must keep their bowel movements smooth and regular. If symptoms of diarrhea (dilute watery stool) appear, immediately drain the abdominal dialysis fluid from the abdomen and reinfuse it after the diarrheal symptoms disappear. If the abdominal dialysis catheter is dislodged or broken, immediately consult a specialist (who has carried out abdominal dialysis) hospital. 11, insist on cleaning the tunnel mouth with saline once a day. 12, Mupirocin ointment can be used to apply regularly to the nasal cavity; it is recommended that if economic conditions permit, some Cordyceps preparations (Bailing capsule or Jin Shui Bao) can be taken regularly to enhance the patient’s immunity and prevent infection.