Lipomatous cysts are medically referred to as epidermoid cysts, and it is not recommended to squeeze epidermoid cysts on the back, as it may lead to infection in the affected area and aggravate the condition. This symptom usually does not require treatment, if the symptoms are serious or the patient’s own needs, under the guidance of the doctor with medication, physical therapy, surgical treatment and other methods. Epidermoid cysts on the back are not recommended to be squeezed by the patient, which can lead to infection if not done properly. Epidermoid cysts are benign lesions that usually have no conscious symptoms and usually do not require treatment. Fusidic acid cream can be applied to the affected area under the supervision of a doctor if the patient needs it. Physical therapy such as laser ablation and electrodesiccation can also be used. Surgical removal is also an option. The prognosis is usually good after treatment. Daily attention should be paid to maintaining a good attitude, keeping the lesions clean and dry, avoiding scratching and friction, and preventing local infection. It is recommended that patients go to the hospital in time, under the guidance of the doctor standardized treatment.