Rectal ulcers and celiac disease can be treated with oral salazosulfapyridine enteric tablets, flavopiridol medication or enema treatment. Rectal ulcers and erosions are caused by long-term inflammation of the rectal mucosa, resulting in mucosal ulcers and erosions, which are mainly manifested by abdominal distension, diarrhea, and mucopurulent stools. The drug can decompose amino salicylic acid and sulfapyridine under the action of intestinal micro-ecological environment, which can act on the connective tissue of intestinal wall for a long time to play the role of antibacterial and anti-inflammatory, and can help improve the condition. Berberine hydrochloride, the main component of Flavopiridol, can not only eliminate the inflammation of the intestinal area, but also achieve the effect of Qi regulation and pain relief. Some people can use enemas for treatment, common drugs include safranin solution and allicin, enema treatment not only can reach the lesion directly, but also will not affect the body organs, so the treatment effect is more obvious.