It is best not to drink alcohol for the following reasons: 1, the patient will have obvious pain and swelling when the ankle sprain, drinking will accelerate the vasodilation, making the above clinical manifestations further aggravated, which is not conducive to the recovery of the damaged tissue. 2, if the ankle sprain is open, it also requires debridement and suture surgery, and the perioperative period requires the use of cephalosporin antibiotics to prevent infection. If you drink alcohol, it is easy to produce an allergic reaction to cephalosporin antibiotics and even anaphylaxis, leading to serious consequences and even endangering the patient’s life. Therefore, it is best not to drink alcohol when the ankle sprain is fully recovered and the ankle joint activities are not restricted and the swelling and pain disappears completely. Drinking alcohol again at this time will not affect the ankle injury, otherwise it may produce adverse reactions.