It’s the time of the year when many people are susceptible to colds. Most patients who do not have obvious symptoms will go to the drugstore and buy some cold medicine on their own. But if you often wear contact lenses, you should be careful during the cold. Normal tears consist of a protein layer, an aqueous layer, and a lipid layer. The outermost lipid layer prevents tears from evaporating too quickly and keeps your eyes moist and not dry. Wearing contact lenses can destabilize the lipid layer and make tears evaporate faster. Wearing contact lenses for a long period of time can reduce the secretion and circulation of tears, resulting in dry eyes. Many anti-cold medications contain acetaminophen and histamine antagonists, which can lead to reduced glandular secretion, causing dry mouth, dry eyes, and dry nose. Wearing contact lenses itself can easily cause dry eyes, and if you continue to wear contact lenses during the medication period, it will aggravate the dryness and easily lead to keratitis, conjunctivitis, etc. The actual fact is that during a cold, your own resistance is generally worse than usual, which will also increase the chance of eye infection. Therefore, it is best not to wear contact lenses during a cold. If you experience significant dry eyes during the medication period, you can take some artificial tears to keep your eyes moist.