There are a variety of topical medications for premature ejaculation, commonly used are lidocaine hydrochloride gel, dacronine hydrochloride and so on. Most of the topical medications for the treatment of premature ejaculation are local topical anesthetics, such as lidocaine hydrochloride gel, dacronine hydrochloride, etc. Such medications can temporarily reduce the sensitivity of the glans penis and reduce the transmission of penile excitation to the central nervous system, thus prolonging ejaculation time and improving the effect of premature ejaculation. Lidocaine hydrochloride gel has the potential to cause rapid pulse, increased blood pressure and other adverse reactions, high blood pressure should be used with caution, allergic to this drug is prohibited. Dacronine hydrochloride may cause hot and cold sensations, local numbness, mild headache and other adverse reactions, the past use of this drug allergic reactions occur, is strictly prohibited. Patients should not use local topical anesthetics indiscriminately, must be directed by a professional doctor, and should not be used in large quantities during the use of the drug, so as not to cause the penis can not be normal erection.