A little pain in chest tightness requires consideration of the following possibilities. 1, coronary heart disease, mainly manifested as chest tightness and chest pain after activity, which can radiate to the left posterior wall and left upper arm. It can be relieved after 3-5 minutes of oral quick-acting heart pills and or nitroglycerin, mostly combined with high-risk factors of coronary heart disease, such as hypertension, diabetes, hyperlipidemia, smoking, obesity, etc. 2, respiratory system diseases, such as lung infection can appear chest tightness, chest pain, mostly with fever, cough, coughing sputum, etc., can be diagnosed by checking blood inflammatory index and chest imaging. 3, neurological functional diseases, such as anxiety, chest tightness and chest pain can appear, but organic diseases causing chest tightness and chest pain need to be excluded. 4, other causes of chest tightness and chest pain, such as heart valve disease, cardiac arrhythmia, digestive system diseases, etc. can cause chest tightness and chest pain. That is, to confirm the cause of chest tightness and chest pain, it is recommended to go to a regular hospital for systematic examination and treatment.