Uterine fibroids do not usually cause swelling of the calves. Usually uterine fibroids are more common in gynecological clinics, it is a common and frequent gynecological disease, especially for female patients around 40 years old. Under normal circumstances, uterine fibroids do not cause leg swelling. However, if the fibroid is very large and compresses the blood vessels and lymphatic vessels in the lower abdomen, it may cause leg swelling, but this is relatively rare. Uterine fibroids are the most common benign tumors of the female genitalia, consisting of smooth muscle and connective tissue, and can be divided into uterine body fibroids and cervical fibroids. At present, patients with uterine fibroids can follow the doctor’s instructions and choose between conservative treatment and surgical treatment according to the size of the fibroid and the presence of uncomfortable symptoms. If the patient has a swollen calf, it is recommended to consult a doctor in time, complete the relevant examination, and under the guidance of the doctor to clarify the cause of the disease, targeted treatment.