Yellow and thick nasal mucus in colds is not a sign that the disease is getting better, and targeted treatment should be carried out. If the yellow nasal mucus appears in the cold, and relatively thick, mostly because of the nasal mucosa congestion, edema, inflammatory exudation caused by the consideration of secondary purulent bacterial infection, may be complicated by bronchitis, pneumonia, the condition will be aggravated trend, so can not be regarded as a yellow thick nasal mucus that is the improvement of the condition of the cold. Patients need to go to the hospital internal medicine, can follow the doctor’s instructions to take amoxicillin, clavulanate potassium tablets, penicillin, piperacillin, roxithromycin and other drugs for treatment, usually need to use the drug for more than two weeks, the symptom will be gradually relieved. If there is more yellow thick nasal mucus, nasal saline rinsing should be given. During the recovery period, you should pay attention to rest, eat a reasonable diet, avoid eating spicy and stimulating food, drink more water to promote the body’s metabolism, which will help early recovery.